While injuries are a part of the game of football, they can also be its kryptonite.

Buffalo Bill defensive back Damar Hamlin was in critical condition early Tuesday after his heart stopped following a tackle during the Monday Night Football game against the Cincinnati Bengals. The game was indefinitely postponed.

“Damar Hamlin suffered a cardiac arrest following a hit in our game versus the Bengals,” the Buffalo Bills organization said in a statement. “His heartbeat was restored on the field, and he was transferred to the UC Medical Center for further testing and treatment. He is currently sedated and listed in critical condition.”

Like Hamlin, other prominent players have suffered from severe injuries during games, some ending their careers.

Bo Jackson (Los Angeles Raiders)

The former football player suffered a hip injury after being tackled in a 1990 playoff game against the Cincinnati Bengals. Unfortunately, after the injury, Jackson didn’t play football again. Jackson played in one Pro Bowl game before his injury, according to Bleacher Report.

Sterling Sharpe (Green Bay Packers)